Glycochemical biology
WebSep 17, 2016 · Chemoenzymatic approach served as an alternative method for the synthesis of complex carbohydrate-containing molecules. The use of biosynthetic enzymes not only provides high regioselectivity and stereoselectivity for the formation of glycosidic bonds but also solves the problems of protection and deprotection steps required by … WebGlycosylation is a critical post-translational modification (PTM) that affects the function of proteins and regulates cell signaling, thereby regulating various biological processes. Protein oxygen-N-acetylglucosamine (O-GlcNAc) glycosylation modifications are glycochemical modifications that occur …
Glycochemical biology
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WebThe polysaccharide capsule of Streptococcus pneumoniae constitutes the outermost surface structure of the organism and plays a critical role in virulence. The capsule is the target of current pneumococcal vaccines and glycoconjugates and has important medical and industrial applications. WebSep 17, 2016 · The International Union of Pure and Applied Chemistry (IUPAC) defines glycan as 'synonymous with polysaccharides', meaning compounds consisting of a large number of monosaccharides linked to each other through glycosidic bonds. The term 'glycan' is used to describe the carbohydrate portion of glycoconjugates such as …
WebWe thus developed the next-generation strategy from the glycochemical biology, termed as “Therapeutic In Vivo Synthetic Chemistry”, where the activities of drugs or other bioactive molecules could be elicited without off-targeting problems by directly synthesizing them at the targeted diseases. Information related to the author ... WebThis book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars ...
WebSrinivas Hotha. Professor and Dean (Planning and Communications) Chemistry. Glycochemical Biology. +91-20-25908015. [email protected]. Research Group Website. Explore ways of giving Connect with us. WebNov 1, 2007 · Ulrich Andergassen. Glycosylation is one of the most important posttranslational modifications of proteins and lipids that contributes to the structural diversity of cellular molecules. Enzymes of ...
WebAssociate Professor . Chemistry . Indian Institute of Science Education and Research, Pune
WebApr 5, 2024 · Abstract and Figures Naturally occurring N- glycoproteins exhibit glycoform heterogeneity with respect to N-glycan sequon occupancy (macroheterogeneity) and glycan structure (microheterogeneity).... emotionally distant daily crosswordWebOrganic Chemistry Carbohydrate Chemistry Glycochemical Biology Peptide and Protein Modification. Articles Cited by Public access Co-authors. Title. Sort. Sort by citations Sort by year Sort by title. Cited by. Cited by. Year; Palladium-catalyzed C–H arylation of (benzo) oxazoles or (benzo) thiazoles with aryltrimethylammonium triflates. emotionally disabled studentsWebOct 10, 2016 · His work focuses on carbohydrate chemistry and chemical biology, including the development of novel approaches to glycan synthesis and the acquisition of important cell-surface glycan components together with their biological evaluations. dr amen chocolate barsWebThis book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. Provides detailed discussion on specific topics like oligosaccharide assembly and design of … dr amen clinic atlantaWebSep 17, 2016 · Summary This chapter introduces protecting groups that are commonly and currently utilized in carbohydrate synthesis, the logic of selecting protecting groups, and the concept of orthogonality. It ... emotionally disconnected spouseWebNov 1, 2007 · Request PDF On Nov 1, 2007, Noriko Nagahori and others published [Glycochemical biology] Find, read and cite all the research you need on ResearchGate dr amen clinics australiaWeb开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 emotionally disconnected husband