Plicamine-type alkaloids
WebbWe report herein a nonbiomimetic strategy for the total synthesis of the plicamine‐type alkaloids, zephycarinatines C and D. The key feature of the synthesis was the stereoselective reductive radical ipso‐cyclization using … WebbTotal synthesis of the plicamine‐type alkaloids zephycarinatines C and D has been achieved. The key feature of the synthesis is a stereoselective radical ipso‐cyclization using visible‐light‐mediated photoredox catalysis.
Plicamine-type alkaloids
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WebbT. GOEZLER's 6 research works with 60 citations and 249 reads, including: ChemInform Abstract: The Gracilines: A Novel Subgroup of the Amaryllidaceae Alkaloids Webb1 okt. 2024 · Plicamine-type alkaloids have been found in the phylogenetically unrelated genera Galanthus, Narcissus, Cyrtanthus and Zephyranthes.53,207,213,215,226 The …
Webb17 juni 2002 · Total synthesis of the amaryllidaceae alkaloid (+)-plicamine and its unnatural enantiomer by using solid-supported reagents and scavengers in a multistep … Webb1 okt. 2024 · The results showed plicamine-type alkaloids 1 and 2 with ketone of C-6 exhibited more potent cytotoxicity (IC 50 values from 9.2 to 10.6 and from 12.4 to 13.9 …
WebbWe report herein a nonbiomimetic strategy for the total synthesis of the plicamine-type alkaloids zephycarinatines C and D. The key feature of the synthesis is a stereoselective reductive radical ipso-cyclization using visible-light-mediated photoredox catalysis.This cyclization enabled the construction of a 6,6-spirocyclic core structure through the … Webb27 jan. 2024 · Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (¹H- ¹H COSY, HMQC, and HMBC) NMR spectroscopy, in …
Webb1 maj 2014 · Biosynthetic pathway of the nine basic Amaryllidaceae alkaloid types and a new plicamine-type alkaloid according to Eichhorn et al. (1998), Bastida et al. (2006), and de Andrade et al. (2012). Amaryllidaceous plants have a long tradition of medical uses, and their alkaloids have been the subject of many reviews ( Bastida et al., 2006 , Bastida et …
Webb12 apr. 2024 · Uncarialines A-E (1–5), five undescribed monoterpene indole alkaloids, together with five known analogues were obtained from the stems of Uncaria rhynchophylla. Alkaloids 1–3 were unique 3,4-seco-tricyclic alkaloids with a 6/5/10 ring system, while 4 and 5 possessed a rare rearranged scaffold originated from … ninja by richard meyer violin 2Webb1 sep. 2024 · Cytotoxic and anti-inflammatory active plicamine alkaloids from Zephyranthes grandiflora. ... (1-6), including three novel 11,12-seco-plicamine-type alkaloids. The structures of the isolated compounds were established based on 1D and 2D (1 H 1 H COSY, HMQC, and HMBC) NMR spectroscopy, ... nu flow liningWebb12 sep. 2024 · Eleven new alkaloids (1–11), classified as the 12-acetylplicamine (1), N-deformyl-seco-plicamine (2), plicamine (3–6), 4a-epi-plicamine (7), seco-plicamine (8), … nuflow riceWebbAll the alkaloids were in vitro evaluated for their cytotoxic activities against six glioma cell lines (CHG-5, SH-SY5Y, SHG-44, U251, U343, and GL15). Alkaloids 2 and 3 exhibited … nuflow pipe relining ukWebb22 sep. 2024 · Eleven new alkaloids (1-11), classified as the 12-acetylplicamine (1), N-deformyl-seco-plicamine (2), plicamine (3-6), 4a-epi-plicamine (7), seco-plicamine (8), … nu flow softwareWebb1 maj 2024 · Isocarbostyril alkaloids is a kind of alkaloid does not contain basic nitrogen atoms and is represented by hydroxylated benzophenanthridone or isoquinolinone types … nuflow rockhamptonWebbThe minor alkaloids, (+)-plicamine (I) and (-)-secoplicamine (II), from Galanthus plicatus subsp. byzantinus are the first examples of dinitrogenous alkaloids where the oxygen atom in position 7 of the basic tazettine mol. has been replaced by a nitrogen atom substituted by a pendant 4-hydroxyphenethyl moiety. O O N NMe OH H H O O N O N OH H ... nuflow stl